Hello,

If you are getting following error while doing any updates on the server

rpmdb: Program version 4.2 doesn’t match environment version
error: db4 error(22) from dbenv->open: Invalid argument
error: cannot open Packages index using db3 - Invalid argument (22)
error: cannot open Packages database in /var/lib/rpm

Then to fix that do as per below step.
1. Check for processes holding the rpm database open (usually in MUTEX/FUTEX states):
lsof | grep /var/lib/rpm

If it finds any, kill -9 them all.

2. Delete any temporary DB files:

rm -fv /var/lib/rpm/__*

3. Rebuild your RPM database:

rpm –rebuilddb -v -v

If you still have problems, a reboot is probably quickest, then repeat steps 2 and 3 above.

Hopefully it will fix he problem.

Enjoy..